Heidel, Florian H.: search on Z-Library

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1

Internal tandem duplication mutations in the tyrosine kinase domain of FLT3 display a higher oncogenic potential than the activation loop D835Y mutation

Marhäll, Alissa, Heidel, Florian, Fischer, Thomas, Rönnstrand, Lars

Journal:

Annals of Hematology

Year:

2018

Language:

english

File:

PDF, 2.12 MB

english, 2018

2

Clonal evolution patterns in acute myeloid leukemia with NPM1 mutation

Cocciardi, Sibylle, Dolnik, Anna, Kapp-Schwoerer, Silke, Rücker, Frank G., Lux, Susanne, Blätte, Tamara J., Skambraks, Sabrina, Krönke, Jan, Heidel, Florian H., Schnöder, Tina M., Corbacioglu, Andrea,

Journal:

Nature Communications

Year:

2019

Language:

english

File:

PDF, 1.23 MB

english, 2019

3

Results of a multicenter phase II trial for older patients with c-Kit-positive acute myeloid leukemia (AML) and high-risk myelodysplastic syndrome (HR-MDS) using low-dose Ara-C and Imatinib

Florian Heidel, Jorge Cortes, Frank G. Rücker, Walter Aulitzky, Laurie Letvak, Thomas Kindler, Christoph Huber, Hartmut Döhner, Hagop Kantarjian, Thomas Fischer

Journal:

Year:

2007

Language:

english

File:

PDF, 154 KB

english, 2007

4

Analysis of anti-proliferative and chemosensitizing effects of sunitinib on human esophagogastric cancer cells: Synergistic interaction with vandetanib via inhibition of multi-receptor tyrosine kinase pathways

Orestis Lyros, Annett Mueller, Florian Heidel, Carl C. Schimanski, Ines Gockel, Peter R. Galle, Hauke Lang, Markus Moehler

Journal:

International Journal of Cancer

Year:

2010

Language:

english

File:

PDF, 1.27 MB

english, 2010

5

The kinase inhibitor LS104 induces apoptosis, enhances cytotoxic effects of chemotherapeutic drugs and is targeting the receptor tyrosine kinase FLT3 in acute myeloid leukemia

Stefan Kasper, Frank Breitenbuecher, Yvette Hoehn, Florian Heidel, Daniel B. Lipka, Boyka Markova, Christoph Huber, Thomas Kindler, Thomas Fischer

Journal:

Leukemia Research

Year:

2008

Language:

english

File:

PDF, 1.01 MB

english, 2008

6

Entwicklung von Tyrosinkinase-Inhibitoren bei hämatologischen Neoplasien. FLT3 und JAK2 als therapeutische Targets

Daniel Lipka, Florian Heidel, Christoph Huber, Thomas Fischer

Journal:

Pharmazie in unserer Zeit

Year:

2008

Language:

german

File:

PDF, 580 KB

german, 2008

7

3,4-Diarylmaleimides—a novel class of kinase inhibitors—effectively induce apoptosis in FLT3-ITD-dependent cells

Florian H. Heidel, Thomas S. Mack, Elena Razumovskaya, Marie-Christine Blum, Daniel B. Lipka, Anne Ballaschk, Jan-Peter Kramb, Stanislav Plutizki, Lars Rönnstrand, Gerd Dannhardt, Thomas Fischer

Journal:

Annals of Hematology

Year:

2012

Language:

english

File:

PDF, 1.47 MB

english, 2012

8

Focal progression in patients with gastrointestinal stromal tumors after initial response to imatinib mesylate: a three-center-based study of 38 patients

Salah-Eddin Al-Batran, Joerg Thomas Hartmann, Florian Heidel, Jan Stoehlmacher, Eva Wardelmann, Claudius Dechow, Markus Düx, Jacob Robert Izbicki, Thomas Kraus, Thomas Fischer, Elke Jäger

Journal:

Year:

2007

Language:

english

File:

PDF, 326 KB

english, 2007

9

Self-renewal related signaling in myeloid leukemia stem cells

Florian H. Heidel, Brenton G. Mar, Scott A. Armstrong

Journal:

International Journal of Hematology

Year:

2011

Language:

english

File:

PDF, 385 KB

english, 2011

10

Bis(1H-indol-2-yl)methanones are effective inhibitors of FLT3-ITD tyrosine kinase and partially overcome resistance to PKC412A in vitro

Florian Heidel, Daniel B. Lipka, Fian K. Mirea, Siavosh Mahboobi, Rebekka Grundler, Rama K. Kancha, Justus Duyster, Michael Naumann, Christoph Huber, Frank D. Böhmer, Thomas Fischer

Journal:

British Journal of Haematology

Year:

2009

Language:

english

File:

PDF, 423 KB

english, 2009

11

Biased distribution of chromosomal breakpoints involving the MLL gene in infants versus children and adults with t(4;11) ALL

Reichel, Martin, Gillert, Esther, Angermüller, Sieglinde, Hensel, Jan Patrick, Heidel, Florian, Lode, Martin, Leis, Thomas, Biondi, Andrea, Haas, Oskar A, Strehl, Sabine

Journal:

Year:

2001

Language:

english

File:

PDF, 173 KB

english, 2001

12

Ponatinib may overcome resistance of FLT3-ITD harbouring additional point mutations, notably the previously refractory F691I mutation

Elisabeth Zirm, Bärbel Spies-Weisshart, Florian Heidel, Ulf Schnetzke, Frank-Dietmar Böhmer, Andreas Hochhaus, Thomas Fischer, Sebastian Scholl

Journal:

British Journal of Haematology

Year:

2012

Language:

english

File:

PDF, 486 KB

english, 2012

13

Severe paraneoplastic pemphigus in a patient with follicular lymphoma

Christian Krogel, Thomas Fischer, Florian Heidel

Journal:

European Journal of Haematology

Year:

2010

Language:

english

File:

PDF, 156 KB

english, 2010

14

Genetic and Pharmacologic Inhibition of β-Catenin Targets Imatinib-Resistant Leukemia Stem Cells in CML

Florian H. Heidel, Lars Bullinger, Zhaohui Feng, Zhu Wang, Tobias A. Neff, Lauren Stein, Demetrios Kalaitzidis, Steven W. Lane, Scott A. Armstrong

Journal:

Year:

2012

Language:

english

File:

PDF, 1.21 MB

english, 2012

15

Expression of protein-tyrosine phosphatases in Acute Myeloid Leukemia cells:FLT3 ITD sustains high levels of DUSP6 expression

Deepika Arora, Susanne Köthe, Monique van den Eijnden, Rob Hooft van Huijsduijnen, Florian Heidel, Thomas Fischer, Sebastian Scholl, Benjamin Tölle, Sylvia-Annette Böhmer, Johan Lennartsson, Fabienne

Journal:

Cell Communication and Signaling

Year:

2012

Language:

english

File:

PDF, 536 KB

english, 2012

16

Intracellular Retention of ABL Kinase Inhibitors Determines Commitment to Apoptosis in CML Cells

Lipka, Daniel B., Wagner, Marie-Christine, Dziadosz, Marek, Schnöder, Tina, Heidel, Florian, Schemionek, Mirle, Melo, Junia V., Kindler, Thomas, Müller-Tidow, Carsten, Koschmieder, Steffen, Fischer, T

Journal:

Year:

2012

Language:

english

File:

PDF, 1.63 MB

english, 2012

17

T1162 Analysis of Antiproliferative and Chemosensitizing Effects of Sunitinib on Human Esophagogastric Cancer Cells: Synergistic Interaction With Vandetanib via Inhibition of Multireceptor Tyrosine Kinase Pathways

Lyros, Orestis, Mueller, Annett, Heidel, Florian, Schimanski, Carl Christoph, Gockel, Ines, Galle, Peter R., Lang, Hauke, Moehler, Markus

Journal:

Gastroenterology

Year:

2010

Language:

english

File:

PDF, 98 KB

english, 2010

18

Germ and Hematology: Underlying Disease Influences Diversity of Germ Spectra and Antibiotic Therapy

Enrico Schalk, MD, Ina Tammer, MD, Florian H. Heidel, MD

Journal:

Infection Control and Hospital Epidemiology

Year:

2014

Language:

english

File:

PDF, 204 KB

english, 2014

19

Novel Bis(1 H -indol-2-yl)methanones as Potent Inhibitors of FLT3 and Platelet-Derived Growth Factor Receptor Tyrosine Kinase

Mahboobi, Siavosh, Uecker, Andrea, Sellmer, Andreas, Cénac, Christophe, Höcher, Heymo, Pongratz, Herwig, Eichhorn, Emerich, Hufsky, Harald, Trümpler, Antje, Sicker, Marit, Heidel, Florian, Fischer, Th

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 448 KB

english, 2006

20

Telomerase Inhibition Effectively Targets Mouse and Human AML Stem Cells and Delays Relapse following Chemotherapy

Bruedigam, Claudia, Bagger, Frederik O., Heidel, Florian H., Paine Kuhn, Catherine, Guignes, Solene, Song, Axia, Austin, Rebecca, Vu, Therese, Lee, Erwin, Riyat, Sarbjit, Moore, Andrew S., Lock, Richa

Journal:

Year:

2014

Language:

english

File:

PDF, 2.61 MB

english, 2014

21

Defective podocyte insulin signalling through p85-XBP1 promotes ATF6-dependent maladaptive ER-stress response in diabetic nephropathy

Madhusudhan, Thati, Wang, Hongjie, Dong, Wei, Ghosh, Sanchita, Bock, Fabian, Thangapandi, Veera Raghavan, Ranjan, Satish, Wolter, Juliane, Kohli, Shrey, Shahzad, Khurrum, Heidel, Florian, Krueger, Mar

Journal:

Nature Communications

Year:

2015

Language:

english

File:

PDF, 5.26 MB

english, 2015

22

Prediction of central venous catheter–related bloodstream infections (CRBSIs) in patients with haematologic malignancies using a modified Infection Probability Score (mIPS)

Schalk, Enrico, Hanus, Lynn, Färber, Jacqueline, Fischer, Thomas, Heidel, Florian H.

Journal:

Annals of Hematology

Year:

2015

Language:

english

File:

PDF, 181 KB

english, 2015

23

Distinct and non-overlapping functions of Llgl1 and scribble in hematopoietic stem cells

Mohr, Juliane, Frey, Stephanie, Bullinger, Lars, Schnoeder, Tina M., Weinert, Soenke, Huber, Tobias B., Kaehne, Thilo, Armstrong, Scott A., Fischer, Thomas, Heidel, Florian H.

Journal:

Experimental Hematology

Year:

2015

Language:

english

File:

PDF, 53 KB

english, 2015

24

Leukemogenic potency of the novel FLT3-N676K mutant

Huang, Kezhi, Yang, Min, Pan, Zengkai, Heidel, Florian H., Scherr, Michaela, Eder, Matthias, Fischer, Thomas, Büsche, Guntram, Welte, Karl, von Neuhoff, Nils, Ganser, Arnold, Li, Zhixiong

Journal:

Annals of Hematology

Year:

2016

Language:

english

File:

PDF, 1.56 MB

english, 2016

25

Central Venous Catheter–Related Bloodstream Infections in Obese Hematologic Patients

Schalk, Enrico, Färber, Jacqueline, Fischer, Thomas, Heidel, Florian H.

Journal:

Infection Control and Hospital Epidemiology

Year:

2015

Language:

english

File:

PDF, 62 KB

english, 2015

26

Leukemic mastopathy

Schalk, Enrico, Heidel, Florian H.

Journal:

International Journal of Hematology

Year:

2016

Language:

english

File:

PDF, 544 KB

english, 2016

27

Characteristics and treatment of polycythemia vera patients in clinical practice: a multicenter chart review on 1476 individuals in Germany

Jentsch-Ullrich, Kathleen, Eberhardt, Judith, Zeremski, Vanja, Koehler, Michael, Wolleschak, Denise, Heidel, Florian H.

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

2016

Language:

english

File:

PDF, 876 KB

english, 2016

28

RSK-mediated nuclear accumulation of the cold-shock Y-box protein-1 controls proliferation of T cells and T-ALL blasts

Gieseler-Halbach, Steffi, Meltendorf, Stefan, Pierau, Mandy, Weinert, Soenke, Heidel, Florian H, Fischer, Thomas, Handschuh, Juliane, Braun-Dullaeus, Ruediger C, Schrappe, Martin, Lindquist, Jonathan

Journal:

Cell Death & Differentiation

Year:

2017

Language:

english

File:

PDF, 4.24 MB

english, 2017

29

Hacking the stem cell niche

Lane, Steven W., Heidel, Florian H.

Journal:

Year:

2017

Language:

english

File:

PDF, 583 KB

english, 2017

30

Managing myeloproliferative neoplasms evidence based on the ELN treatment recommendations 2018

Heidel, Florian H., Gale, Robert Peter, Hochhaus, Andreas

Journal:

Year:

2018

Language:

english

File:

PDF, 516 KB

english, 2018

31

Dysregulation of chemokine receptor expression and function in leukocytes from ALS patients

Perner, Caroline, Perner, Florian, Stubendorff, Beatrice, Förster, Martin, Witte, Otto W., Heidel, Florian H., Prell, Tino, Grosskreutz, Julian

Journal:

Journal of Neuroinflammation

Year:

2018

Language:

english

File:

PDF, 930 KB

english, 2018

32

Loss of DEP-1 (Ptprj) promotes myeloproliferative disease in FLT3-ITD acute myeloid leukemia

Kresinsky, Anne, Bauer, Reinhard, Schnöder, Tina M., Berg, Tobias, Meyer, Daria, Ast, Volker, König, Rainer, Serve, Hubert, Heidel, Florian H., Böhmer, Frank-D., Müller, Jörg P.

Journal:

Year:

2018

Language:

english

File:

PDF, 2.41 MB

english, 2018

33

Ruxolitinib in elderly patients with myelofibrosis: impact of age and genotype. A multicentre study on 291 elderly patients

Palandri, Francesca, Catani, Lucia, Bonifacio, Massimiliano, Benevolo, Giulia, Heidel, Florian, Palumbo, Giuseppe A., Crugnola, Monica, Abruzzese, Elisabetta, Bartoletti, Daniela, Polverelli, Nicola,

Journal:

British Journal of Haematology

Year:

2018

Language:

english

File:

PDF, 680 KB

english, 2018

34

Questions arising on phlebotomy in polycythemia vera: prophylactic measures to reduce thromboembolic events require patient-focused decisions

Heidel, Florian H., Al-Ali, Haifa-Kathrin, Hirt, Carsten, Kämpfe, Dietrich, Jentsch-Ullrich, Kathleen, Junghanss, Christian, Nowak, Ralf, Schwarzer, Andreas, Spohn, Claudia, Vucinic, Vladan, Hochhaus,

Journal:

Year:

2018

Language:

english

File:

PDF, 242 KB

english, 2018

35

Epigenetic Erosion in Adult Stem Cells: Drivers and Passengers of Aging

Kosan, Christian, Heidel, Florian, Godmann, Maren, Bierhoff, Holger

Journal:

Year:

2018

Language:

english

File:

PDF, 1.05 MB

english, 2018

36

Randomized comparison of low dose cytarabine with or without glasdegib in patients with newly diagnosed acute myeloid leukemia or high-risk myelodysplastic syndrome

Cortes, Jorge E., Heidel, Florian H., Hellmann, Andrzej, Fiedler, Walter, Smith, B. Douglas, Robak, Tadeusz, Montesinos, Pau, Pollyea, Daniel A., DesJardins, Pierre, Ottmann, Oliver, Ma, Weidong Wendy

Journal:

Year:

2018

Language:

english

File:

PDF, 1.35 MB

english, 2018

37

Risikoadaptierte Therapie chronischer BCR-ABL1-negativer myeloproliferativer Neoplasien; Risk-adapted treatment of chronic BCR-ABL1 negative myeloproliferative neoplasms;

Heidel, Florian H., Döhner, Konstanze

Journal:

Year:

2019

Language:

german

File:

PDF, 369 KB

german, 2019

38

Plasma VCAM1 levels correlate with disease severity in Parkinson’s disease

Perner, Caroline, Perner, Florian, Gaur, Nayana, Zimmermann, Silke, Witte, Otto W., Heidel, Florian H., Grosskreutz, Julian, Prell, Tino

Journal:

Journal of Neuroinflammation

Year:

2019

Language:

english

File:

PDF, 1.05 MB

english, 2019

39

[IEEE 2018 IEEE International Conference on Internet of Things (iThings) and IEEE Green Computing and Communications (GreenCom) and IEEE Cyber, Physical and Social Computing (CPSCom) and IEEE Smart Data (SmartData) - Halifax, NS, Canada (2018.7.30-2018.8.3)] 2018 IEEE International Conference on Internet of Things (iThings) and IEEE Green Computing and Communications (GreenCom) and IEEE Cyber, Physical and Social Computing (CPSCom) and IEEE Smart Data (SmartData) - Webchain: Verifiable Citations and References for the World Wide Web

Rohrer, Elias, Heidel, Steffen, Tschorsch, Florian

Year:

2018

Language:

english

File:

PDF, 529 KB

english, 2018

40

Life after ruxolitinib: Reasons for discontinuation, impact of disease phase, and outcomes in 218 patients with myelofibrosis

Palandri, Francesca, Breccia, Massimo, Bonifacio, Massimiliano, Polverelli, Nicola, Elli, Elena M., Benevolo, Giulia, Tiribelli, Mario, Abruzzese, Elisabetta, Iurlo, Alessandra, Heidel, Florian H., Be

Journal:

Year:

2019

File:

PDF, 593 KB

2019

41

Risikoadaptierte Therapie chronischer BCR-ABL1-negativer MPN*

Heidel, Florian H., Döhner, Konstanze

Journal:

InFo Hämatologie + Onkologie

Year:

2019

File:

PDF, 502 KB

2019

42

SIRT7: an influence factor in healthy aging and the development of age-dependent myeloid stem-cell disorders

Kaiser, Alexander, Schmidt, Martin, Huber, Otmar, Frietsch, Jochen J., Scholl, Sebastian, Heidel, Florian H., Hochhaus, Andreas, MÃ¼ller, JÃ¶rg P., Ernst, Thomas

Journal:

Year:

2020

Language:

english

File:

PDF, 1.55 MB

english, 2020

43

Prevalence and dynamics of clonal hematopoiesis caused by leukemia-associated mutations in elderly individuals without hematologic disorders

Midic, Danica, Rinke, Jenny, Perner, Florian, MÃ¼ller, Violetta, Hinze, Anna, Pester, Frank, Landschulze, JÃ¼rgen, Ernst, Jana, Gruhn, Bernd, Matziolis, Georg, Heidel, Florian H., Hochhaus, Andreas, E

Journal:

Year:

2020

File:

PDF, 776 KB

2020

44

Survival outcomes and clinical benefit in patients with acute myeloid leukemia treated with glasdegib and low-dose cytarabine according to response to therapy

Cortes, Jorge E., Heidel, Florian H., Fiedler, Walter, Smith, B. Douglas, Robak, Tadeusz, Montesinos, Pau, Candoni, Anna, Leber, Brian, Sekeres, Mikkael A., Pollyea, Daniel A., Ferdinand, Roxanne, Ma,

Journal:

Journal of Hematology & Oncology

Year:

2020

File:

PDF, 1.22 MB

2020

45

PLCÎ³1 suppression promotes the adaptation of KRAS-mutant lung adenocarcinomas to hypoxia

Saliakoura, Maria, Rossi Sebastiano, Matteo, Pozzato, Chiara, Heidel, Florian H., SchnÃ¶der, Tina M., Savic Prince, Spasenija, Bubendorf, Lukas, Pinton, Paolo, A. Schmid, Ralph, Baumgartner, Johanna,

Journal:

Nature Cell Biology

Year:

2020

File:

PDF, 17.15 MB

2020

46

Antimicrobial Prodrug Activation by the Staphylococcal Glyoxalase GloB

Mikati, Marwa O., Miller, Justin J., Osbourn, Damon M., Barekatain, Yasaman, Ghebremichael, Naomi, Shah, Ishaan T., Burnham, Carey-Ann D., Heidel, Kenneth M., Yan, Victoria C., Muller, Florian L., Dow

Journal:

ACS Infectious Diseases

Year:

2020

File:

PDF, 4.29 MB

2020

47

Interferon alpha for essential thrombocythemia during 34 high-risk pregnancies: outcome and safety

Schrickel, Lukas, Heidel, Florian H., Sadjadian, Parvis, Becker, Tatjana, Kolatzki, Vera, Hochhaus, Andreas, Griesshammer, Martin, Wille, Kai

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

2020

File:

PDF, 626 KB

2020

48

Activating JAK-mutations confer resistance to FLT3 kinase inhibitors in FLT3-ITD positive AML in vitro and in vivo

Rummelt, Christoph, Gorantla, Sivahari P., Meggendorfer, Manja, Charlet, Anne, Endres, Cornelia, DÃ¶hner, Konstanze, Heidel, Florian H., Fischer, Thomas, Haferlach, Torsten, Duyster, Justus, von Bubno

Journal:

Year:

2020

File:

PDF, 1.58 MB

2020

49

Molecular Mechanisms of Resistance to FLT3 Inhibitors in Acute Myeloid Leukemia: Ongoing Challenges and Future Treatments

Scholl, Sebastian, Fleischmann, Maximilian, Schnetzke, Ulf, Heidel, Florian H.

Journal:

Year:

2020

File:

PDF, 1.01 MB

2020

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